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In biology and specifically, genetics, the term hybrid has several meanings, all referring to the offspring of sexual reproduction.

  1. In general usage, hybrid is synonymous with heterozygous: any offspring resulting from the mating of two distinctly homozygous individuals
  2. a genetic hybrid carries two different alleles of the same gene
  3. a structural hybrid results from the fusion of gametes that have differing structure in at least one chromosome, as a result of structural abnormalities
  4. a numerical hybrid results from the fusion of gametes having different haploid numbers of chromosomes
  5. a permanent hybrid is a situation where only the heterozygous genotype occurs, because all homozygous combinations are lethal.

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